Avidity as a criterion for diagnosis of human strongyloidiasis increases specificity of IgG ELISA.

Larissa Rodrigues Bosqui,Henrique Tomaz Gonzaga,Maria do Rosário de Fátima Gonçalves-Pires,Fabiana Martins de Paula,Ricardo Sergio Almeida,Wander Rogério Pavanelli,Ivete Conchon-Costa,Julia Maria Costa-Cruz,Idessania Nazareth da Costa

Diagnostic Microbiology and Infectious Disease（2017）

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摘要

This study evaluates the inclusion of the IgG avidity index in ELISA to detect anti-Strongyloides stercoralis IgG. The ELISA index revealed 70% of specificity. With the inclusion of screening AI, specificity increased to 80%. IgG avidity complemented traditional IgG ELISA by eliminating some of the suspected or false positive cases.

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关键词

Strongyloidiasis,Cross-reaction,Avidity-ELISA,Strongyloides sp.

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