Discovery of BMS-961955, an Allosteric Inhibitor of the Hepatitis C Virus NS5B Polymerase
Barbara Zhizhen Zheng,Stanley V. D'Andrea,Umesh Hanumegowda,Jay O. Knipe,Kathy Mosure,Xiaoliang Zhuo,Julie A. Lemm,Mengping Liu,Karen L. Rigat,Ying-Kai Wang,Hua Fang, Chris Poronsky,Jingfang Cutrone,Dauh-Rurng Wu,Pirama Nayagam Arunachalam, T. J. Balapragalathan, Arunachalam Arumugam,Arvind Mathur,Nicholas A. Meanwell,Min Gao,Susan B. Roberts,John F. Kadow Bioorganic & medicinal chemistry letters(2017)
关键词
HCV NS5B,Polymerase,Cyclopropyl-fused indolobenzazepine,Metabolic stability,Direct-acting antiviral agent,Antiviral agent
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