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Biomarkers for Early Stage of Acute Respiratory Distress Syndrome in Septic Patients: Surfactant Protein D and Clara Cell Protein

Critical care(2013)

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Abstract
The injury of alveolar epithelium and endothelium is the basis of pathogenesis for the early stage of acute respiratory distress syndrome (ARDS). A prompt detection of this injury will provide us with a possibility for early ARDS diagnosis and treatment. Currently no biomarkers of alveolar epithelial injury are clinically available. The purpose of our study was to investigate the role of surfactant protein D (SPD) and Clara cell protein (CCP) as biomarkers of early ARDS.
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Key words
Acute Respiratory Distress Syndrome,Septic Patient,Receiver Operating Curf,Surfactant Protein,Alveolar Epithelium
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