Profile of Molecular Mutations in Pfdhfr, Pfdhps, Pfmdr1, and Pfcrt Genes of Plasmodium Falciparum Related to Resistance to Different Anti-Malarial Drugs in the Bata District (equatorial Guinea)
Malaria journal(2017)
摘要
The emergence of drug resistance in Plasmodium falciparum has been a major contributor to the global burden of malaria. Drug resistance complicates treatment, and it is one of the most important problems in malaria control. This study assessed the level of mutations in P. falciparum genes, pfdhfr, pfdhps, pfmdr1, and pfcrt, related to resistance to different anti-malarial drugs, in the Continental Region of Equatorial Guinea, after 8 years of implementing artesunate combination therapies as the first-line treatment.
更多查看译文
关键词
Equatorial Guinea,Malaria,P. falciparum,Resistance,Mutations,Antimalarial drugs
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要