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Discovery of Imidazopyridazines As Potent Pim-1/2 Kinase Inhibitors

Ryan P. Wurz,Christine Sastri,Derin C. D'Amico,Brad Herberich,Claire L. M. Jackson,Liping H. Pettus,Andrew S. Tasker,Bin Wu,Nadia Guerrero,J. Russell Lipford,Jeffrey T. Winston,Yajing Yang,Paul Wang,Yen Nguyen,Kristin L. Andrews,Xin Huang,Matthew R. Lee,Christopher Mohr,J. D. Zhang,Darren L. Reid,Yang Xu,Yihong Zhou,Hui-Ling Wang

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2016）

Cited 19|Views78
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Key words
Pim kinase,Kinase inhibitor,Oncology,Proliferation,Hematologic cancer,Multiple myeloma
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