Estimated glomerular filtration rate calculated using different creatinine and cystatin based formulas in prediction of trough plasma Dabigtran concentration.

•The Glomerular filtration rate (eGFR) was estimated, in 100 patients treated with Dabigatran (DAB), using creatinine (CKD-EPIcreat, CG and MDRD) and cystatin (CKD-EPIcys) based formulas.•DAB that had been administered in accordance with CKD-EPIcreat eGFR:150mg TD for eGFR >50ml/min and 110mg TD for eGFR 30-50ml/min.•Trough DAB plasma concentration was related with CRE-eGFR and CYS-eGFR. We observed a better (p<0.05) correlation with CYS-eGFR.•In patients chronically treated with DAB for thromboprophylaxis in non valvular atrial fibrillation, evaluation of eGFR using a cystatine base formula should be considered.