In Silico Predictions and in Vivo Results of Drug–Drug Interactions by Ketoconazole and Verapamil on AZD1305, a Combined Ion Channel Blocker and a Sensitive CYP3A4 Substrate

Susanne Johansson,Boel Lofberg,Maria Aunes, Helen Lunde,Lars Frison,Nils Edvardsson,Marie Cullberg

Clinical pharmacology in drug development（2016）

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Simcyp,PBPK,AZD1305,metabolic drug-drug interactions,CYP3A4

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