Visualizing chaperone-assisted protein folding

Scott Horowitz,Loïc Salmon,Philipp Koldewey,Logan S Ahlstrom,Raoul Martin,Shu Quan,Pavel V Afonine,Henry van den Bedem,Lili Wang,Qingping Xu,Raymond C Trievel,Charles L Brooks III,James C A Bardwell

Nature Structural & Molecular Biology（2016）

引用 45|浏览19

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摘要

READ is a new crystallographic approach to visualize conformational ensembles of heterogeneous and dynamic molecules. READ is applied here to structurally characterize the various folding states of client Im7 bound to chaperone Spy.

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关键词

Chaperones,X-ray crystallography,Life Sciences,general,Biochemistry,Protein Structure,Membrane Biology,Biological Microscopy

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