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Design of a hyperstable 60-subunit protein icosahedron

Yang Hsia,Jacob B. Bale,Shane Gonen,Dan Shi,William Sheffler,Kimberly K. Fong,Una Nattermann,Chunfu Xu,Po-Ssu Huang,Rashmi Ravichandran,Sue Yi,Trisha N. Davis,Tamir Gonen,Neil P. King,David Baker

NATURE（2016）

Cited 429|Views26
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Abstract
The computational design of an extremely stable icosahedral self-assembling protein nanocage is presented; the icosahedron should be useful for applications ranging from calibrating fluorescence microscopy to drug delivery.
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Key words
Protein design,Biomaterials
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