Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder
NATURE NEUROSCIENCE(2016)
摘要
utism spectrum disorder is a complex disease with a strong genetic basis that remains under-characterized by current genetics studies. Here, the authors use a computational approach based on a human brain-specific gene network to predict autism-associated genes across the genome and further delineate their functional and developmental characteristics.
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关键词
Data integration,Machine learning,Autism spectrum disorders,Functional genomics
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