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Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist.

Haiyan Wang,Shanbao Cai,Barbara J Bailey,M Reza Saadatzadeh,Jixin Ding,Eva Tonsing-Carter,Taxiarchis M Georgiadis,T Zachary Gunter,Eric C Long,Robert E Minto, Kevin R Gordon,Stephanie E Sen,Wenjing Cai,Jacob A Eitel,David L Waning,Lauren R Bringman,Clark D Wells, Mary E Murray,Jann N Sarkaria,Lawrence M Gelbert,David R Jones,Aaron A Cohen-Gadol,Lindsey D Mayo,Harlan E Shannon,Karen E Pollok

JOURNAL OF NEUROSURGERY（2016）

引用 30|浏览45
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关键词
glioblastoma,temozolomide,DNA repair,p53,MDM2,combination therapy,patient-derived xenograft,MDM2 inhibitor,oncology
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