Simple Conversion of Fully Protected Amino Acids to Zwitterions

Junliang Hao,Matt Reinhard,Steven S. Henry,Eric P. Seest,Matthew D. Belvo,James A. Monn

Tetrahedron letters（2012）

引用 8|浏览23

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摘要

An operationally simple and efficient method under mild acidic conditions was developed to convert fully protected amino acids to the corresponding zwitterions without either isoelectric precipitation or ion exchange chromatography.

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关键词

mGlu receptors,Amino acids deprotection,Zwitterions,Microwave-assisted synthesis

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