P02.07: Adverse perinatal outcome in fetuses with normal nuchal translucency

The purpose of this retrospective study is to evaluate the perinatal outcome in pregnancies with fetuses with normal nuchal translucency. This retrospective study included 2165 ultrasound control risk chromosomal abnormalities were the antenatal department at Alexandra Hospital in which the NT was below the 95th percentile in a period of 2 years (2010-2011). During this period, 2165 first trimester combined test in which Nuchal Translucency had a value less than the 95th percentile for the corresponding crown-rump length were performed in our hospital. Full outcome was obtained in 1991 pregnancies (93%). In 1893 (95.5%) of pregnancies overall estimated risk was low, while in 98 cases (4.5%) the risk for a chromosomal abnormality increased due to other pathological indicators, primarily biochemical. These embryos were tested by invasive precedures (CVS or Amniocentesis). Among them five pregnancies with chromosomal abnormalities (two with trisomy 21, two trisomy 18 and one with S Kleinefelter) were identified. Nuchal translucency scan is a screening test with high sensitivity and specificity for chromosomal abnormalities such as trisomies 21, 18 and 13 also can give information about serious anatomical abnormalities incompatible with life. However, the sensitivity is low for other chromosomal abnormalities, especially the sex chromosomes whose frequency increases with age. P02.07: Table 1. Adverse outcome