Immune responses against hepatitis C virus genotype 3a virus-like particles in mice: A novel VLP prime-adenovirus boost strategy

Anuj Kumar,Soma Das,Ranajoy Mullick,Priyanka Lahiri,Ranjitha Tatineni,Debashree Goswami,P K Bhat,Anjali A Karande

Vaccine（2016）

引用 21|浏览15

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摘要

•Generated VLP based vaccine against HCV genotype-3a and 1b.•Novel heterologous prime boost strategy eliciting high antibody and T cell response.•Combined regimen of VLP followed by recombinant adenovirus could more effectively inhibit HCV infection.

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EDTA,ELISA,GAPDH,gt,HCV,HCV-LPs,IRES,NP40,PBS,PMSF,RT-PCR,SCID/uPA,TEM,VLPs

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