Serological Targeted Analysis of an ITIH4 Peptide Isoform: A Preterm Birth Biomarker and Its Associated SNP Implications

Zhou Tan,Zhongkai Hu, Emily Y. Cai,Cantas Alev, Ting Yang, Zhen Li,Joyce Sung, Yasser Yehia El-Sayed,Gary M. Shaw,David K. Stevenson,Atul J. Butte,Guojun Sheng,Karl G. Sylvester,Harvey J. Cohen, Xuefeng B. Ling

Journal of Genetics and Genomics（2015）

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摘要

Over 11% of all pregnancies in the US result in preterm birth,greatly contributing to perinatal morbidity and mortality（Goldenberg and Rouse,1998）.Preterm birth etiologies remain largely unknown,and effective prevention methods have yet to be developed.The use of biofluid（e.g.,serum or urine）for the analysis of the naturally occurring peptidome

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