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P16-18. Regulatory T Cell Frequencies Correlate with T Cell Activation in Chronic HIV-1 Infection

Retrovirology(2009)

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摘要
Background Regulatory T cells (Tregs) are potent modulators of immunity and may have an impact on T cell regulation and activation in the setting of HIV-1 infection. However, studies on Tregs in HIV-1 infection have shown divergent results and the exact role of Tregs in HIV-1 infection remains poorly understood. We here investigated Treg frequencies, immune activation and HIV-1 specific immunity in elite controllers (EC) and chronic progressors.
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关键词
Cell Activation,Immune Activation,Specific Immunity,Treg Frequency,Elite Controller
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