Influence of Iodinated Contrast Media and Paramagnetic Contrast Media on Changes in Uptake Counts Of99mtc
Journal of magnetics(2014)
摘要
The purpose of this study is to figure out how uptake counts of technetium (Tc-99m) among radioisotopes in the human body are affected if computed tomography (CT), magnetic resonance imaging (MRI) and isotope examination are performed consecutively. Tc-99m isotope material, iodinated contrast media for CT and paramagnetic contrast media for magnetic resonance (MR) were used as experimental materials. First, Tc-99m was added to 4 cc normal saline in a test tube. Then, 2 cc of CT contrast media such as Iopamidol and Dotarem were diluted with 2 cc normal saline, and 2cc of IVIRI contrast media such as Primovist and Gadovist were diluted with 2 cc normal saline. Each distributed contrast media was a total of 4 cc and included 10m Ci of 99"Tc. A gamma camera, a LEHR (Low energy high resolution) collimator and a pin-hole coffimator were used for image acquisition. Image acquisition was repeated a total of 6 times and 120 frames were obtained and uptake counts of Tc-99m were measured (from this procedure). In this study, as a result of measuring the uptake counts of Tc-99m using the LEHR collimator, the uptake counts were less measured in all contrast media than normal saline as a reference. In particular, the lowest uptake counts were measured when Gadovist, contrast media for MIRE, was used. However, the result of measuring the uptake counts of Tc-99m using the pin-hole collimator showed higher uptake counts in all contrast media, except for Iopamidol, than normal saline as a reference. The highest uptake counts were measured particularly when Primovist, contrast media for MIRE, was used. In performing the gamma camera examination using contrast media and Tc-99m, it is considered significant to check the changes in the uptake counts to improve various diagnosis values.
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关键词
CT contrast media,MR contrast media,Tc-99m isotope,Uptake ratio
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