Effects of Hydrogen Sulphide on Heme Oxigenase Activity in TNBS Induced Colitis

K Kupai,Z Szalai, M Korsós,Z Baráth,S Török,R Szabó,A Csonka,L Daruka,A Pósa,C Varga

Zeitschrift für Gastroenterologie（2014）

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摘要

Hydrogen sulfide (H2S) is an endogenous mediator that relaxes vascular smooth muscle, exhibits several antiinflammatory activities and contributes to protection. Specially, we investigated the beneficial effects of H2S and whether heme-oxigenases (HO) are involved in the H2S-induced colonal cytoprotection against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats.

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