2316 DOES THE USE OF URETERAL STENTS IN RENAL TRANSPLANT ALLOGRAFTS INCREASE THE RISK OF MULTI-DRUG RESISTANT URINARY TRACT INFECTIONS OR DECREASE LONG TERM FUNCTION OF THE ALLOGRAFT?

You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation, Renal Vascular Surgery (II)1 Apr 20132316 DOES THE USE OF URETERAL STENTS IN RENAL TRANSPLANT ALLOGRAFTS INCREASE THE RISK OF MULTI-DRUG RESISTANT URINARY TRACT INFECTIONS OR DECREASE LONG TERM FUNCTION OF THE ALLOGRAFT? Trisha Fleet, Hannah Kerr, Donald Wenner, Yitong Liu, Susan Paine, Antonia Harford, and Michael Davis Trisha FleetTrisha Fleet Albuquerque, NM More articles by this author , Hannah KerrHannah Kerr Albuquerque, NM More articles by this author , Donald WennerDonald Wenner Albuquerque, NM More articles by this author , Yitong LiuYitong Liu Albuquerque, NM More articles by this author , Susan PaineSusan Paine Albuquerque, NM More articles by this author , Antonia HarfordAntonia Harford Albuquerque, NM More articles by this author , and Michael DavisMichael Davis Albuquerque, NM More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2257AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Post renal transplant infectious complications are largely due to urinary tract infections (UTIs). We determined whether the use of a stent increased the risk of developing a multi-drug resistant urinary tract infection in renal transplant patients or affected long term function of the allograft. METHODS We retrospectively analyzed our transplant cases from 2006-2009 (N=172). We divided our cohort into stented or non-stented. We analyzed the cases for development of first post transplant UTI. We further analyzed these positive urine cultures for the presence of multidrug resistance. Of the patients that developed infections we looked at gender, race, ethnicity, preoperative GU anatomic anomalies, and postoperative complications and whether these variables had any significance in the development of postoperative multidrug resistant UTI. Stents were removed at 3 weeks posttransplant. Comparisons of variables between the two cohorts were evaluated using the SAS statistical software. T-test and Chi square were utilized to compare the 2 cohorts with p< 0.05 considered significant. RESULTS Our data analysis found that there was no significant difference in the development of a multidrug resistant UTI in stented versus non-stented patients. Factors having significance in posttransplant multidrug resistant UTI development were female gender (p=0.02) and postoperative complications (p=0.001). Patients with prior GU abnormalities had an increased incidence of postoperative UTI however this did not reach statistical significance. There was no significant difference by race or age. The graft function was the same whether patients had a stent or no stent. CONCLUSIONS Our data shows that the risk of development of a multidrug resistant UTI was not increased by the use of a stent at the time of transplant. The risk of multidrug resistant UTI is increased if the patient is female, has had prior GU anomalies, or had postoperative complications. Stented (n= 117) Non-stented (n= 55) p value UTI (n= 94) 63 (53.8%) 31 (56.4%) 0.66 MDRO UTI (n= 63) 40 (63.5%) 23 (41.8%) 0.56 3 Month eGFR Mean (+/−SD) 64.8 (21.9) 65.1 (17.0) 0.93 12 Month eGFR Mean (+/−SD) 65.9 (20.8) 64.2 (21.7) 0.63 24 Month eGFR Mean (+/−SD) 64.4 (21.3) 65.8 (26.0) 0.73 © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e950 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Trisha Fleet Albuquerque, NM More articles by this author Hannah Kerr Albuquerque, NM More articles by this author Donald Wenner Albuquerque, NM More articles by this author Yitong Liu Albuquerque, NM More articles by this author Susan Paine Albuquerque, NM More articles by this author Antonia Harford Albuquerque, NM More articles by this author Michael Davis Albuquerque, NM More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...