Induction of VZV-Specific Effector Memory T-Cell Response by Herpes Zoster Infection after Lung Transplantation

Primary infection with VZV causes varicella, and VZV reactivation results in herpes zoster (HZ). Compared to healthy individuals, the incidence and severity of HZ is higher in transplant recipients. We questioned whether VZV-specific T-cell reactivity is impaired in transplant recipients, and whether this reactivity restores after HZ.