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Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.

Justin K Murray,Y X Qian, Bin Liu,Robin Elliott,Jennifer Aral,Chawon Park, Xiaodong Zhang,Michael Stenkilsson,Kevin Salyers,M Rose,Huan Li, San Yu,K L Andrews,Anne Colombero, Jeremy Scott Werner,Kevin Gaida,E A Sickmier, P Miu,Andrea A Itano,Joseph G Mcgivern,Colin V Gegg,John K Sullivan,L P Miranda

JOURNAL OF MEDICINAL CHEMISTRY（2015）

Cited 40|Views36
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Key words
peptide toxins,optimization channel targets,pharmaceutical optimization,long-lived
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