One-size-fits-all or patient-tailored hemodynamic targets in post-cardiac arrest patients: an observational near-infrared spectroscopy study on cerebral autoregulation

A subgroup of post-CA patients with disturbed cerebral autoregulation might benefit from higher mean arterial pressures (MAPs). We aimed to (1) investigate whether patients with disturbed autoregulation have a worse prognosis, (2) phenotype these patients, (3) define an individual optimal MAP and (4) investigate whether time under this individual optimal MAP is associated with outcome.