There is a correlation between interleukin-1beta and endothelial dysfunction in patients with mTOR inhibitor-eluting stent implantation

Objectives: Patients with mammalian target of rapamycin (mTOR)-inhibitor drug-eluting stent (DES) were reported to have impaired coronary endothelial function. There is no non-invasive biomarker of coronary endothelial dysfunction. Interleukin (IL)-1beta is known to cause of endothelial dysfunction. We examined whether IL-1beta were associated with coronary endothelial dysfunction after mTOR-inhibitor DES implantation, and to investigate the possible mechanism.