Clinical significance of serum autoantibodies against Ras-like GTPases, RalA, in patients with esophageal squamous cell carcinoma
Esophagus(2016)
摘要
The Ras-like GTPases, RalA and RalB are members of the Ras superfamily of small
GTPases. Aberrant activation of Ral is a major cause of human tumorigenesis induced by oncogenic Ras. Serum anti-RalA antibodies are induced in esophageal carcinoma patients. However, detailed comparisons of their pathological characteristics are unavailable, and conventional serum markers have not been well evaluated.
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关键词
RalA,Serum autoantibody,Tumor marker,Esophageal cancer,ELISA
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