Immunogenicity of Recurrent Mutations in MYD88 and EZH2 in Non-Hodgkin Lymphomas

Julie S Nielsen,Andrew R Chang,Darin A Wick, Colin G Sedgwick,Zusheng Zong,Andrew J Mungall,Bemuluyigza Baraki,Natalie Kinloch,Zabrina L Brumme,Steven P Treon,Joseph M Connors,Randy D Gascoyne, John R Webb,Brian R Berry,Ryan D Morin,Nicol Macpherson,Brad H Nelson

Journal for immunotherapy of cancer（2015）

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摘要

Meeting abstracts A fundamental challenge in cancer genomics is to design effective, personalized treatments based on the mutational profiles of tumors. Pharmacological targeting of the numerous aberrant pathways found in individual tumors remains exceedingly challenging, but T cell-based therapies

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Lymphoma Patient,Peptide Library,Driver Mutation,Recurrent Mutation,Mutational Profile

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