Manifestasi Klinis Infeksi Virus Chikungunya pada Kejadian Luar Biasa di Indonesia

Chikungunya is a re-emerging disease that caused by alphavirus family Togaviridae. Chikungunya also can often caused outbreak in Asia, including Indonesia. Disease characterized by fever accompanied by pain in the joints of the dominant. Chikungunya virus is transmitted by mosquitoes, especially Aedes aegypti, A. Albopictus and Mansoniasp. This study was conducted to identify significant clinical symptoms of chikungunya virus infection. Sampling was carried from Chikungunya outbreak area. Suspected Chikungunya are interviewed and taken blood. Specimens were examined using reverse transcription - polymerase chain reactions (RT-PCR). Interviews were conducted on 111suspected chikungunya from 6 provinces.Clinical symptoms analisys was performed from 28 confirm chikungunya cases based on laboratory result. Chikungunya showed more on the malesex, and the productive age group (64.3%). The most joint pain symptom reported is wristand knee joints (92.9%), followed by the ankle joint (75%) and finger joints (64.3%). Other non-specific clinical symptoms such asheadaches(78.6%), decreased appetite(71.4%), nausea/vomiting(60.7%), feverwith chills(55%), and abdominal pain andvisual impairment(25 and17.9% ). Laboratory results showed 28 positive specimen for Chikungunya. Chikungunya is more common in males and productive age groups, with the joint pain symptoms especially knee and wrist joints followed by non -specific symptoms such as headache, decreased appetite and also nausea/vomiting. Key words : Chikungunya, Outbreak, Clinical symptoms, Indonesia.