K13-Propeller Polymorphisms in Plasmodium Falciparum Isolates from Patients in Mayotte in 2013 and 2014

Marylin Torrentino-Madamet,Louis Collet,Jean Francois Lepere,Nicolas Benoit,Remy Amalvict,Didier Menard,Bruno Pradines

Antimicrobial agents and chemotherapy（2015）

Cited 20|Views4

No score

Abstract

ABSTRACT Plasmodium falciparum isolates were collected from 29 malaria patients treated with artemether-lumefantrine in Mayotte in 2013 and 2014. Twenty-four cases (83%) consisted of imported malaria. Seventeen percent of the isolates presented mutations in one of the six K13-propeller blades (N490H, F495L, N554H/K, and E596G). A total of 23.8% of the isolates from the Union of Comoros showed K13-propeller polymorphisms. Three of the 18 isolates (16.7%) from Grande Comore showed polymorphisms (N490H, N554K, and E596G).

Translated text

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined