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A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA

Christine Schuberth-Wagner,Janos Ludwig, Ann Kristin Bruder,Anna-Maria Herzner, Thomas Zillinger,Marion Goldeck,Tobias Schmidt,Jonathan L. Schmid-Burgk,Romy Kerber,Steven Wolter, Jan-Philip Stuempel,Andreas Roth,Eva Bartok,Christian Drosten,Christoph Coch,Veit Hornung,Winfried Barchet,Beate M. Kuemmerer,Gunther Hartmann,Martin Schlee

Immunity（2015）

Cited 204|Views49
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Key words
mRNA,cap,2′O-methyl,5′-triphosphate RNA,immune recognition of RNA,virus,RIG-I,MTr1,innate immune tolerance mechanism
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