Interactions of Pluronic nanocarriers with 2D and 3D cell cultures: Effects of PEO block length and aggregation state

Alexandra Arranja,Antonia G. Denkova,Karolina Morawska,Gilles Waton,Sandra van Vlierberghe,Peter Dubruel,François Schosseler,Eduardo Mendes

Journal of Controlled Release（2016）

引用 30|浏览9

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摘要

This work reveals how the physicochemical properties of Pluronic block copolymers influence significantly their interactions with cancer cells, whether in monolayer or spheroid cultures, and how different clinical applications can be foreseen.

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关键词

Pluronic,Unimers,Micelles,Endocytosis,Exocytosis,Tumor spheroids

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