Synthesis and anti-mycobacterial activity of glycosyl sulfamides of arabinofuranose

Organic & Biomolecular Chemistry(2016)

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摘要
A series ofarabino N-glycosyl sulfamides, forced to adopt the furanose form by removal of the 5-hydroxyl group, were synthesised as putative isosteric mimics of decaprenolphosphoarabinose, the donor processed by arabinosyltransferases during mycobacterial cell wall assembly.
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