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Prospective Study of Thromboembolism in 1038 Children with Acute Lymphoblastic Leukemia: a Nordic Society of Pediatric Hematology and Oncology (NOPHO) Study.

Journal of Thrombosis and Haemostasis(2016)

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摘要
Essentials Children with acute lymphoblastic leukemia (ALL) are at risk of thromboembolism (TE). This is a prospective evaluation of the incidence, risk factors and outcomes of TE in 1038 children with ALL. TE occurred in 6.1% of children, with the highest incidence (20.5%) among those aged 15–17 years. A TE‐associated case fatality of 6.4% indicates that TE is a severe complication of ALL treatment.
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关键词
acute lymphoblastic leukemia,asparaginase,children,thromboembolism
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