Effect of IgM-Enriched Immunoglobulin As Adjunctive Therapy in a Patient Following Sepsis after Open Thoracoabdominal Aortic Aneurysm Repair.

DESPITE SUBSTANTIAL ADVANCES in surgical techniques and significant improvement in perioperative care during recent years, open surgical repair of thoracoabdominal aortic aneurysms (ThAAA) remains associated with significant morbidity and mortality. 1 Dayama A, Sugano D, Reeves JG, et al: Early outcomes and perioperative risk assessment in elective open thoracoabdominal aortic aneurysm repair: An analysis of national data over a five-year period. Vascular (In press) Google Scholar Besides surgical complications, this high-risk procedure can be accompanied by respiratory insufficiency with prolonged ventilation, cardiac complications, acute kidney injury, 2 Cowan Jr, J.A. Dimick J.B. Henke P.K. et al. Surgical treatment of intact thoracoabdominal aortic aneurysms in the United States: Hospital and surgeon volume-related outcomes. J Vasc Surg. 2003; 37: 1169-1174 Abstract Full Text Full Text PDF PubMed Scopus (326) Google Scholar spinal cord ischemic complications, visceral organ ischemia, and sepsis/septic shock. If sepsis/septic shock occurs in a patient who has undergone ThAAA open repair, chances for survival are drastically decreased.