No Effect on QT Intervals of Mipomersen, a 2′- O -Methoxyethyl Modified Antisense Oligonucleotide Targeting ApoB-100 Mrna, in a Phase I Dose Escalation Placebo-Controlled Study, and Confirmed by a Thorough QT (tqt) Study, in Healthy Subjects
European journal of clinical pharmacology(2015)
关键词
QT,tQT,Antisense oligonucleotide,Mipomersen,Phase I study
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