Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages
Nature immunology(2015)
摘要
Cd4 expression in helper and cytotoxic T cells is locked in by gene-expression programs that define lineage identity. Littman and colleagues define stage-specific methylation and demethylation events that regulate the heritable expression of Cd4 .
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nature immunology, science
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