NIR-Triggered Drug Delivery by Collagen-Mediated Second Harmonic Generation.

Aoune Barhoumi,Borja Salvador-Culla,Daniel S Kohane

ADVANCED HEALTHCARE MATERIALS（2015）

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摘要

Second harmonic generation is a process through which nonlinear materials such as collagen can absorb two photons and scatter one with twice the energy. Collagen upconverts 730 nm (near-IR) to 365 nm (UV) through second harmonic generation, which cleaves a molecule bound to collagen via a UV-sensitive linker.

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关键词

drug delivery,near-IR,nonlinear optics,photocleavage,second harmonic generation

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