The Cost of Research: a Survey of Participating Sites in a Nationwide Registry.

OBJECTIVE:Much attention has been placed upon decreasing costs of clinical research. However, little has been studied about the effects on research completion.METHODS:A survey was sent to all registry investigators and coordinators to determine the cost of enrollment in a national registry, whether sites had to supplement using their own funds, and whether the cost affected enrollment.RESULTS:Results indicate that a majority of sites supplemented enrollment with their own funding (88%) and diagnoses requiring a lot of time to enroll were avoided.CONCLUSION:This survey showed that reimbursement rates were well below the costs of enrollment.