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Utilizing Physiologically Based Pharmacokinetic Modeling to Inform Formulation and Clinical Development for a Compound with Ph-Dependent Solubility

John Chung,Fernando Alvarez-Nunez,Vincent Chow,Dominick Daurio,John Davis,Michael Dodds,Maurice Emery,Kevin Litwiler,Anne Paccaly,Joanna Peng,Brooke Rock,Larry Wienkers,Charles Yang,Zhigang Yu,Jan Wahlstrom

Journal of pharmaceutical sciences（2015）

Cited 18|Views9
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Key words
absorption,disposition,pharmacokinetics,ADME,physiological model
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