Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ

John R Somoza,David Koditek,Armando G Villaseñor,Nikolai Novikov,Melanie H Wong,Albert Liclican,Weimei Xing,Leanna Lagpacan,Ruth Wang,Brian E Schultz,Giuseppe A Papalia,Dharmaraj Samuel,Latesh Lad,Mary E McGrath

Journal of Biological Chemistry（2015）

Cited 129|Views19

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Key words

Enzyme Kinetics,Enzyme Mechanism,Enzyme Purification,Phosphatidylinositide 3-Kinase (PI 3-Kinase),Surface Plasmon Resonance (SPR),CAL-101,GS-1101,PI3K,PI3Kδ,Zydelig

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