Child and Adolescent Down Syndrome-Associated Leukaemia: the Irish Experience
Irish journal of medical science(2014)
摘要
Down syndrome (DS), the most common syndromic chromosomal abnormality is associated with a unique susceptibility to develop both acute myeloid (ML) and lymphoblastic leukaemia (ALL). These leukaemias differ from the non-DS-related types of leukaemia and are thought to be distinct biological entities.
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关键词
Down syndrome,Acute lymphoblastic leukaemia,Down syndrome myeloid leukaemia,Megakaryoblastic leukaemia,Treatment-related mortality,Prognosis
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