DIPA-family Coiled-Coils Bind Conserved Isoform-Specific Head Domain of P120-Catenin Family: Potential Roles in Hydrocephalus and Heterotopia

Isoform-specific expression of p120 affects cell motility and migration during development and tumor progression. The DIPA coiled-coil protein is a novel binding partner to the conserved isoform 1–specific head domain of p120 family members. Zebrafish data suggest that DIPA is mechanistically linked to p120 isoform–specific function in development.