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Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody

Jon A Kenniston,Ryan R Faucette,Diana Martik,Stephen R Comeau,Allison P Lindberg,Kris J Kopacz,Gregory P Conley, Jie Chen,Malini Viswanathan,Niksa Kastrapeli,Janja Cosic,Shauna Mason,Mike DiLeo,Jan Abendroth,Petr Kuzmic,Robert C Ladner,Thomas E Edwards,Christopher TenHoor,Burt A Adelman,Andrew E Nixon,Daniel J Sexton

Journal of Biological Chemistry（2014）

Cited 95|Views24

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Key words

Antibody Engineering, Enzyme Inhibitor, Inflammation, Kallikrein, Protease

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