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Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors.

Jason D Burch,Kevin Lau,John J Barker,Fred Brookfield,Yong Chen,Yuan Chen,Charles Eigenbrot,Claire Ellebrandt,M Hicham A Ismaili,Adam Johnson,Daniel Kordt,Colin H MacKinnon,Paul A McEwan,Daniel F Ortwine,Daniel B Stein,Xiaolu Wang,Dirk Winkler,Po-Wai Yuen,Yamin Zhang,Ali A Zarrin,Zhonghua Pei

JOURNAL OF MEDICINAL CHEMISTRY（2014）

引用 28|浏览44
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关键词
tetrahydroindazole series,inhibitors,structure-guided,t-cell
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