Discovery And Optimization Of Potent Gpr40 Full Agonists Containing Tricyclic Spirocycles

Yingcai Wang,Jiwen Liu,Paul J. Dransfield,Liusheng Zhu,Zhongyu Wang,Xianyun Jiao,Yongli Su,An-Rong Li,Annie Kasparian,Sean P. Brown,Marc Vimolratana,Xiaohui Du,Ming Yu,Vatee Pattaropong,Jonathan B. Houze,Gayathri Swaminath,Thanhvien Tran,Khanh Nguyen,Qi Guo,Jane Zhang,Run Zhuang,Frank Li,Lynn Miao,Michael D. Bartberger,Tiffany L. Correll,David Chow,Simon Wong,Jian Luo,Daniel Lin,Julio C. Medina

ACS medicinal chemistry letters（2013）

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关键词
am-1638,am-5262,amg 837,ffa1,ffar1,gpr40,full agonist,spirocycles,tricyclic,biomedical research,bioinformatics
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