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Fragment-Based Discovery of 6-Azaindazoles As Inhibitors of Bacterial DNA Ligase

Steven Howard,Nader Amin,Andrew B. Benowitz,Elisabetta Chiarparin,Haifeng Cui,Xiaodong Deng,Tom D. Heightman,David J. Holmes,Anna Hopkins,Jianzhong Huang,Qi Jin,Constantine Kreatsoulas,Agnes C. L. Martin,Frances Massey,Lynn McCloskey,Paul N. Mortenson,Puja Pathuri,Dominic Tisi,Pamela A. Williams

ACS medicinal chemistry letters（2013）

引用 23|浏览30
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关键词
Bacterial DNA ligase,S. aureus,fragment-based drug design,structure based optimization
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