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Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics.

Mustapha Haddach,Michael K Schwaebe,Jerome Michaux,Johnny Nagasawa,Sean E O'Brien,Jeffrey P Whitten,Fabrice Pierre,Pauline Kerdoncuff,Levan Darjania,Ryan Stansfield,Denis Drygin,Kenna Anderes,Chris Proffitt,Josh Bliesath,Adam Siddiqui-Jain,May Omori,Nanni Huser,William G Rice,David M Ryckman

ACS medicinal chemistry letters（2012）

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关键词
cx-5461,rna polymerase i,p53,rrna,bioinformatics,biomedical research
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