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The discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Paul M Scola,Li-Qiang Sun,Alan Xiangdong Wang,Jie Chen,Ny Sin,Brian L Venables,Sing-Yuen Sit,Yan Chen,Anthony Cocuzza,Donna M Bilder,Stanley V D'Andrea,Barbara Zheng,Piyasena Hewawasam,Yong Tu,Jacques Friborg,Paul Falk,Dennis Hernandez,Steven Levine,Chaoqun Chen,Fei Yu,Amy K Sheaffer,Guangzhi Zhai,Diana Barry,Jay O Knipe,Yong-Hae Han,Richard Schartman,Maria Donoso,Kathy Mosure,Michael W Sinz,Tatyana Zvyaga,Andrew C Good,Ramkumar Rajamani,Kevin Kish,Jeffrey Tredup,Herbert E Klei,Qi Gao,Luciano Mueller,Richard J Colonno,Dennis M Grasela,Stephen P Adams,James Loy,Paul C Levesque,Huabin Sun,Hong Shi,Lucy Sun,William Warner,Danshi Li,Jialong Zhu,Nicholas A Meanwell,Fiona McPhee

JOURNAL OF MEDICINAL CHEMISTRY（2014）

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关键词
efficacious ns3 protease inhibitor,asunaprevir,virus
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