Discovery and early clinical evaluation of BMS-605339, a potent and orally efficacious tripeptidic acylsulfonamide NS3 protease inhibitor for the treatment of hepatitis C virus infection. Paul M Scola , Alan Xiangdong Wang , Andrew C Good , Li-Qiang Sun , Keith D Combrink , Jeffrey A Campbell , Jie Chen , Yong Tu , Ny Sin , Brian L Venables , Sing-Yuen Sit , Yan Chen , Anthony Cocuzza , Donna M Bilder , Stanley D'Andrea , Barbara Zheng , Piyasena Hewawasam , Min Ding , Jan Thuring , Jianqing Li , Dennis Hernandez , Fei Yu , Paul Falk , Guangzhi Zhai , Amy K Sheaffer , Chaoqun Chen , Min S Lee , Diana Barry , Jay O Knipe , Wenying Li , Yong-Hae Han , Susan Jenkins , Christoph Gesenberg , Qi Gao , Michael W Sinz , Kenneth S Santone , Tatyana Zvyaga , Ramkumar Rajamani , Herbert E Klei , Richard J Colonno , Dennis M Grasela , Eric Hughes , Caly Chien , Stephen Adams , Paul C Levesque , Danshi Li , Jialong Zhu , Nicholas A Meanwell , Fiona McPhee JOURNAL OF MEDICINAL CHEMISTRY（2014）
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