GluK1 Antagonists from 6-(Carboxy)phenyl Decahydroisoquinoline Derivatives. SAR and Evaluation of a Prodrug Strategy for Oral Efficacy in Pain Models
Jose A. Martinez-Perez,Smriti Iyengar,Harlan E. Shannon,David Bleakman,Andrew Alt,Brian M. Arnold,Michael G. Bell,Thomas J. Bleisch,Ana M. Castano,Miriam Del Prado,Esteban Dominguez,Ana M. Escribano,Sandra A. Filla,Ken H. Ho,Kevin J. Hudziak,Carrie K. Jones,Ana Mateo,Brian M. Mathes,Edward L. Mattiuz,Ann Marie L. Ogden,Rosa Maria A. Simmons,Douglas R. Stack,Robert E. Stratford,Mark A. Winter,Zhipei Wu,Paul L. Ornstein Bioorganic & medicinal chemistry letters（2013）
关键词
Pain,Decahydroisoquinolines,GluK1 antagonists,GluA2,Prodrug
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