Impact of Food and the Proton Pump Inhibitor Rabeprazole on the Pharmacokinetics of GDC-0941 in Healthy Volunteers: Bench to Bedside Investigation of Ph-Dependent Solubility.
Molecular Pharmaceutics（2013）
关键词
gastric pH,acid-reducing agents (ARA),proton pump inhibitor (PPI),H2-receptor antagonists (H2RA),drug absorption,physicochemical,drug-drug interaction (DDI),oral anti-cancer therapy,molecular targeted agents,drug development
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