HOXA10 Mrna Expression and Promoter DNA Methylation in Female Pig Offspring after in Utero Estradiol-17Β Exposure.

Veronika L. Pistek,Rainer W. Fürst,Heike Kliem,Stefan Bauersachs,Heinrich H.D. Meyer, Susanne E. Ulbrich

The Journal of Steroid Biochemistry and Molecular Biology（2013）

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Abstract
•We analyzed HOXA10 in porcine female offspring after in utero exposure to E2.•Neither HOXA10 mRNA expression nor promoter DNA methylation was affected.•mRNA expression correlated with DNA methylation in prepubertal, but not adult gilts.•HOXA10 may be subjected to developmental tissue specific regulation.
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Key words
Bp,DES,BPA,E2,EDC,MS-HRM,P4
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